Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269996 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL29922652 | 0.87 | MAPT (0.39) | ALDH1A1KDM4ECYP3A4HTTTDP1 | |
| SCHEMBL21799996 | 0.87 | MAPT (0.39) | ALDH1A1KDM4ECYP3A4HTTTDP1 | |
| SCHEMBL28009674 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL31427597 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL8379148 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL31294508 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL3248985 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL27352538 | 0.77 | PLK1 (0.52) | ALDH1A1KDM4ETSHRCYP3A4HTT | |
| SCHEMBL21800072 | 0.76 | HDAC3 (0.39) | ALDH1A1KDM4EHTTCA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |
| EP-0041140-B1 | LIQUID PREPARATIONS OF OXIDATION DYES | BASF Aktiengesellschaft (DE) | 1984-10-31 | — | — | EP | disclosed |
| US-4378969-A | IRON TETRAAZA(14)ANNULENE CATALYST, BROWN SHADES | BASF AKTIENGESELLSCHAFT (DE) | 1983-04-05 | — | — | US | disclosed |
| EP-0041140-A2 | Liquid preparations of oxidation dyes | BASF Aktiengesellschaft (DE) | 1981-12-09 | — | — | EP | disclosed |