Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129694 | 0.76 | TSHR (0.44) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL11059931 | 0.76 | MEN1 (0.45) | CYP3A4ALOX15MEN1KMT2ALMNA | |
| SCHEMBL2622207 | 0.75 | HRH1 (0.55) | MTORRAB9AGRM7TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL27495530 | 0.75 | MEN1 (0.46) | CYP3A4ALOX15MEN1KMT2ALMNA | |
| SCHEMBL21625228 | 0.72 | SRC (0.45) | LMNA | |
| SCHEMBL2433381 | 0.70 | KCNN4 (0.42) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL30741205 | 0.69 | MTOR (0.57) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL3281034 | 0.69 | MTOR (0.57) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL28905650 | 0.67 | MTOR (0.39) | MTORRAB9AGRM7TSHRCYP3A4 | |
| SCHEMBL27168294 | 0.67 | LMNA (0.43) | TSHRMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023317-A1 | CODING COMBINATORIAL LIBRARIES WITH FLUORINE TAGS | Abbott Laboratories (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999019344-A1 | CODING COMBINATORIAL LIBRARIES WITH FLUORINE TAGS | ABBOTT LABORATORIES (US) | 1999-04-22 | — | — | WO | disclosed |