SCHEMBL8102895

SCHEMBL8102895

O=C1NC(Cc2c[nH]cn2)C(=O)NC1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.45
HDAC8 Q9BY41 2/20 0.41
PLA2G10 O15496 1/20 0.40
PLA2G5 P39877 1/20 0.40
GAA P10253 2/20 0.38
POLB P06746 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
TACR2 P21452 5/20 0.38
MMP1 P03956 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
JAK2 O60674 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479076 1.00 HRH3 (0.45) HRH3HDAC8PLA2G10PLA2G5GAA
SCHEMBL8102889 1.00 HRH3 (0.45) HRH3HDAC8PLA2G10PLA2G5GAA
SCHEMBL9665668 1.00 HRH3 (0.45) HRH3HDAC8PLA2G10PLA2G5GAA
SCHEMBL9666858 1.00 HRH3 (0.45) HRH3HDAC8PLA2G10PLA2G5GAA
SCHEMBL6753882 1.00 HRH3 (0.45) HRH3HDAC8PLA2G10PLA2G5GAA
SCHEMBL9667791 0.89 HRH3 (0.51) HRH3CYP1A2CYP2C19
SCHEMBL9667779 0.89 HRH3 (0.51) HRH3CYP1A2CYP2C19
SCHEMBL9478999 0.87
SCHEMBL9666883 0.87
SCHEMBL9666919 0.85 CAPN1 (0.39) HRH3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749738-B1 VISCOELASTIC, SOLID SURFACTANT COMPOSITION HENKEL AG & CO KGAA (DE) 2024-08-14 EP claimed
EP-3749739-B1 DETERGENT COMPOSITION HAVING A FLOW LIMIT HENKEL AG & CO KGAA (DE) 2023-06-21 EP claimed
CN-100429223-C Process for producing cyclo (D-phenylpropyl-D-group) dipeptide NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-10-29 CN claimed
CN-1557834-A Process for producing cyclo (D-phenylpropyl-D-group) dipeptide �Ͼ���ҵ��ѧ 2004-12-29 CN claimed
EP-0132392-B1 ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1992-01-02 EP claimed
EP-0132392-A2 Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols ICI AUSTRALIA LIMITED (AU) 1985-01-30 EP claimed
US-12584080-B2 Gel-like shaped body for fragrancing textiles during the washing process HENKEL AG & CO. KGAA (DE) 2026-03-24 US disclosed
US-12514356-B2 Perfume-containing shaped body HENKEL AG & CO. KGAA (DE) 2026-01-06 US disclosed
US-12441963-B2 Low-molecular gelling agent as fragrant substance dispensing system HENKEL AG & CO. KGAA (DE) 2025-10-14 US disclosed
US-20250243434-A1 METHOD FOR MANUFACTURING A DETERGENT PORTION UNIT HENKEL AG & CO. KGAA (DE) 2025-07-31 US disclosed
US-20250243435-A1 A METHOD FOR MANUFACTURING A DETERGENT PORTION UNIT HENKEL AG & CO. KGAA (DE) 2025-07-31 US disclosed
US-20250223524-A1 METHOD FOR MANUFACTURING A DETERGENT PORTION UNIT HENKEL AG & CO. KGAA (DE) 2025-07-10 US disclosed
US-20250223525-A1 PROCESS FOR MANUFACTURING A DETERGENT PORTION UNIT HENKEL AG & CO. KGAA (DE) 2025-07-10 US disclosed
US-20200115654-A1 Gel-Like Shaped Body For Fragrancing Textiles During The Washing Process HENKEL AG & CO. KGAA (DE) 2020-04-16 US disclosed
CN-100429223-C Process for producing cyclo (D-phenylpropyl-D-group) dipeptide NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-10-29 CN disclosed
CN-1557834-A Process for producing cyclo (D-phenylpropyl-D-group) dipeptide �Ͼ���ҵ��ѧ 2004-12-29 CN disclosed
JP-2000159739-A RECOVERY OF CATALYST SUMITOMO CHEM CO LTD 2000-06-13 JP disclosed
EP-0132392-B1 ASYMMETRIC SYNTHESIS OF ALPHA-SUBSTITUTED-ALPHA-CYANOMETHYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1992-01-02 EP disclosed
EP-0304954-A2 Cyclic dipeptide enantiomers ICI AUSTRALIA LIMITED (AU) 1989-03-01 EP disclosed
EP-0132392-A2 Asymmetric synthesis of alpha-substituted-alpha-cyanomethyl alcohols ICI AUSTRALIA LIMITED (AU) 1985-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584080-B2 Gel-like shaped body for fragrancing textiles during the washing process ADH1C, AKR1C3, AKR1C4 HRH3 1771/4885HDAC8 4005/4885PLA2G10 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.