Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.65 |
| ▸ | MAST3 | O60307 | 3/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8111037 | 0.85 | MAPK8 (0.69) | MAPK8MAST3MAPK9 | |
| SCHEMBL8112516 | 0.85 | MAPK8 (0.65) | MAPK8MAST3 | |
| SCHEMBL8103022 | 0.84 | MAPK8 (0.71) | MAPK8MAST3MAPK9 | |
| SCHEMBL8111186 | 0.84 | MAPK8 (0.67) | MAPK8MAST3 | |
| SCHEMBL8102748 | 0.81 | MAPK8 (0.69) | MAPK8 | |
| SCHEMBL8112512 | 0.80 | MAPK8 (0.71) | MAPK8 | |
| SCHEMBL8118642 | 0.80 | MAPK8 (0.97) | MAPK8 | |
| SCHEMBL8117091 | 0.79 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL3496822 | 0.72 | MAPK8 (0.46) | MAPK8 | |
| SCHEMBL119071 | 0.71 | HTR3E (0.39) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865442-B1 | IMIDAZO[1,2-a]QUINOXALIN-4-AMINES ACTIVE AS ADENOSINE ANTAGONISTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FOSCAMA BIOMED CHIM FARMA (IT) | 2000-07-05 | — | — | EP | disclosed |