Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103006 | 1.00 | KIF11 (0.47) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL12032029 | 0.94 | KIF11 (0.44) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL12032265 | 0.94 | KIF11 (0.44) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL12032250 | 0.92 | KIF11 (0.40) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL15744295 | 0.91 | CYP2C9 (0.45) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9074856 | 0.91 | CYP2C9 (0.45) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL14526002 | 0.90 | KIF11 (0.40) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6454469 | 0.90 | KIF11 (0.40) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL6454471 | 0.90 | KIF11 (0.40) | KIF11CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL13002327 | 0.89 | KDM1A (0.48) | KIF11CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628532-B1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GMBH (DE) | 2000-01-19 | — | — | EP | disclosed |
| US-5641429-A | STABLE COMPOUNDS HAVING LOW VISCOSITY AND HIGH DIELECTRIC ANISOTROPY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-06-24 | — | — | US | disclosed |
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5487845-A | ELECTROOPTICAL DISPLAY ELEMENTS; CHEMICAL, HEAT AND LIGHT STABILITY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-01-30 | — | — | US | disclosed |
| EP-0441932-B1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0628532-A1 | Fluorobenzole derivatives and mesomorphous medium | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0441932-A1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM. | MERCK PATENT GMBH (DE) | 1991-08-21 | — | — | EP | disclosed |
| WO-1991003450-A1 | FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-21 | — | — | WO | disclosed |