SCHEMBL8103104

SCHEMBL8103104

Cc1cc(C)c2c(=O)c3ccccc3sc2c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.65
ALDH1A1 P00352 5/20 0.65
POLB P06746 3/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
GAA P10253 1/20 0.65
L3MBTL1 Q9Y468 2/20 0.58
LMNA P02545 2/20 0.58
HCRTR1 O43613 1/20 0.58
MAOA P21397 2/20 0.50
MAOB P27338 1/20 0.50
APP P05067 1/20 0.43
CHRM2 P08172 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CHRM1 P11229 1/20 0.43
DRD1 P21728 1/20 0.43
TBXA2R P21731 1/20 0.43
SLC6A2 P23975 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3160057 0.88 ALDH1A1 (0.62) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8089980 0.82 MAPT (0.51) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8078642 0.81 MAPT (0.57) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL31120507 0.81 MAPT (0.50) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL10059336 0.80 MAPT (0.58) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL29528353 0.79 ALDH1A1 (1.00) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL2335275 0.79 ALDH1A1 (1.00) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL30913888 0.78 MAPT (0.57) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL28800533 0.78 MAPT (0.57) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL30161909 0.78 MAPT (0.61) MAPTALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1132831-C Liquid thioxanthone photoinitiators FIRST CHEMICAL CORP. (US) 2003-12-31 CN disclosed
CN-1314903-A Liquid thioxanthone photoinitiators FIRST CHEMICAL CORP (US) 2001-09-26 CN disclosed
US-6025408-A Liquid thioxanthone photoinitiators FIRST CHEMICAL CORPORATION (US) 2000-02-15 US disclosed
WO-1998042697-A2 LIQUID THIOXANTHONE PHOTOINITIATORS FIRST CHEMICAL CORPORATION (US) 1998-10-01 WO disclosed