Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114059 | 1.00 | PNMT (0.41) | PNMTCHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6941499 | 1.00 | PNMT (0.41) | PNMTCHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6949428 | 1.00 | PNMT (0.41) | PNMTCHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL8110861 | 0.98 | CHRNA7 (0.39) | PNMTCHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6947533 | 0.98 | CHRNA7 (0.39) | PNMTCHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6944691 | 0.92 | CHRNA7 (0.41) | PNMTCHRNA7HRH3TSHRCASP1 | |
| SCHEMBL8114527 | 0.92 | CHRNA7 (0.41) | PNMTCHRNA7HRH3TSHRCASP1 | |
| SCHEMBL8109720 | 0.79 | CHRNA7 (0.38) | CHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6946834 | 0.79 | CHRNA7 (0.38) | CHRNA7HRH3ALDH1A1TSHR | |
| SCHEMBL6939591 | 0.79 | CHRNA7 (0.38) | CHRNA7HRH3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |