Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547718 | 0.79 | TRPV1 (0.39) | TRPV1TRPA1SPHK1 | |
| SCHEMBL4866475 | 0.75 | SPHK1 (0.56) | TRPV1TRPA1SPHK1 | |
| SCHEMBL1132564 | 0.72 | — | — | |
| SCHEMBL5270800 | 0.72 | SPHK1 (0.69) | TRPV1TRPA1SPHK1 | |
| SCHEMBL24168582 | 0.71 | — | — | |
| SCHEMBL1129564 | 0.71 | — | — | |
| SCHEMBL10896888 | 0.70 | TSHR (0.43) | TRPV1TRPA1SPHK1 | |
| SCHEMBL9586340 | 0.70 | — | — | |
| SCHEMBL29020429 | 0.70 | TRPV1 (0.41) | TRPV1TRPA1SPHK1 | |
| SCHEMBL5683591 | 0.70 | TRPV1 (0.41) | TRPV1TRPA1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999002990-A1 | COMBINATORIAL PROCESS FOR PREPARING FUSED SUBSTITUTED PYRIMIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |