Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103390 | 1.00 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| Iodide SCHEMBL5949266 | 0.99 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| Iodide SCHEMBL5949270 | 0.99 | MAPT (0.38) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8103317 | 0.79 | TSHR (0.41) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8103321 | 0.79 | TSHR (0.41) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| Iodide SCHEMBL5949583 | 0.78 | SMN1; SMN2 (0.41) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| Iodide SCHEMBL5949586 | 0.78 | SMN1; SMN2 (0.41) | MAPTRAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8992020 | 0.73 | PHGDH (0.51) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8992021 | 0.73 | PHGDH (0.51) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10420577 | 0.73 | PHGDH (0.51) | MAPTRAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |