Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992021 | 1.00 | PHGDH (0.51) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL10420577 | 1.00 | PHGDH (0.51) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL10419001 | 0.84 | RAB9A (0.53) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL8884084 | 0.84 | RAB9A (0.53) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL24528362 | 0.83 | TSHR (0.46) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL11482047 | 0.82 | HPGD (0.52) | HPGDGAAFAAHCYP2C9ALDH1A1 | |
| SCHEMBL11482052 | 0.82 | HPGD (0.52) | HPGDGAAFAAHCYP2C9ALDH1A1 | |
| SCHEMBL11475019 | 0.81 | HPGD (0.55) | HPGDGAAFAAHCYP2C9ALDH1A1 | |
| SCHEMBL8884271 | 0.80 | PHGDH (0.44) | PHGDHHPGDTSHRSMN1; SMN2GAA | |
| SCHEMBL14144562 | 0.80 | RAB9A (0.56) | HPGDSMN1; SMN2GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496943-A | USING UNSATURATED ACYLISOCYANATE COMPOUNDS TO FORM OXAZOLINES, PYRANS WITH AMINOCARBONYLHETERO SUBSTITUTION AND GLUTARIMIDE DERIVATIVES AS CHEMICAL INTERMEDIATES | NIPPON PAINT CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0503958-A2 | Heterocyclic compounds and their production | Nippon Paint Co., Ltd. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4602088-A | RHODIUM CARBONYL-PHOSPHINE CATALYST | TEXACO INC. (US) | 1986-07-22 | — | — | US | disclosed |