Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | FPR2 | P25090 | 11/20 | 0.35 |
| ▸ | FPR1 | P21462 | 5/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446800 | 0.92 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8101929 | 0.91 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8109424 | 0.91 | ITGB3 (0.66) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Hydrochloric Acid SCHEMBL8101680 | 0.91 | ITGB3 (0.56) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7454376 | 0.90 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7445983 | 0.89 | ITGB3 (0.77) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7450166 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8109527 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7455251 | 0.89 | ITGB3 (0.61) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Water SCHEMBL7449648 | 0.88 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |