Isopropylamine

Isopropylamine

SCHEMBL8103474

CC(C)C(C)N.CC(C)N

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC7A5 Q01650 1/20 0.33
LAP3 P28838 1/20 0.32
MAPK1 P28482 1/20 0.31
TRPV1 Q8NER1 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56475 0.94
SCHEMBL56276 0.94
SCHEMBL3609 0.94
Hydrochloric Acid SCHEMBL4919255 0.89
Hydrochloric Acid SCHEMBL4917263 0.89
Fluoride SCHEMBL25337975 0.89
Hydrochloric Acid SCHEMBL5741254 0.89
Hydrochloric Acid SCHEMBL6267532 0.89
Isopropylamine SCHEMBL3156399 0.82 ALDH1A1 (0.62) ALDH1A1TSHRHSD17B10SLC7A5LAP3
Isopropylamine SCHEMBL2909 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973936-A1 COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS ELI LILLY AND COMPANY (US) 2000-01-26 EP disclosed
EP-0938676-A1 COMBINATORIAL PROCESS FOR PREPARING THIAZOLIDINONE LIBRARIES ELI LILLY AND COMPANY (US) 1999-09-01 EP disclosed
WO-1999002990-A1 COMBINATORIAL PROCESS FOR PREPARING FUSED SUBSTITUTED PYRIMIDINE LIBRARIES ELI LILLY AND COMPANY (US) 1999-01-21 WO disclosed
WO-1998046786-A1 COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS ELI LILLY AND COMPANY (US) 1998-10-22 WO disclosed
WO-1998021584-A1 COMBINATORIAL PROCESS FOR PREPARING THIAZOLIDINONE LIBRARIES ELI LILLY AND COMPANY (US) 1998-05-22 WO disclosed