Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102933 | 1.00 | SIGMAR1 (1.00) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL7533190 | 1.00 | SIGMAR1 (1.00) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL8097030 | 1.00 | SIGMAR1 (1.00) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL8105906 | 0.99 | SIGMAR1 (0.97) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL9102909 | 0.99 | SIGMAR1 (0.97) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL467010 | 0.99 | SIGMAR1 (0.97) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL8104932 | 0.92 | SIGMAR1 (0.85) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL8103642 | 0.92 | SIGMAR1 (0.85) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL8098647 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HIF1ADRD2DRD3KCNH2 | |
| SCHEMBL8098642 | 0.87 | SIGMAR1 (0.77) | SIGMAR1HIF1ADRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |