Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 5/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123500 | 0.87 | — | — | |
| SCHEMBL12492435 | 0.87 | — | — | |
| SCHEMBL787988 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL19371443 | 0.85 | SLC1A3 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| L-Alaninol SCHEMBL8352335 | 0.83 | SLC1A1 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| SCHEMBL19411426 | 0.81 | SLC7A5 (0.58) | SLC7A5ALDH1A1TSHRMAPK1SLC1A3 | |
| SCHEMBL11143927 | 0.79 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Alanine SCHEMBL27717605 | 0.78 | ALDH1A1 (0.63) | SLC7A5ALDH1A1TSHRMAPK1SLC1A3 | |
| SCHEMBL14743945 | 0.76 | RNPEP (0.46) | SLC7A5ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| L-Alaninol SCHEMBL8342003 | 0.73 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |