Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | FPR2 | P25090 | 10/20 | 0.34 |
| ▸ | FPR1 | P21462 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455056 | 1.00 | ITGB3 (0.63) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL7450577 | 0.92 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL7445983 | 0.91 | ITGB3 (0.77) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7449988 | 0.91 | ITGB3 (0.69) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7448472 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL7454726 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL7455251 | 0.90 | ITGB3 (0.61) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL7446800 | 0.90 | ITGB3 (0.64) | ITGB3ITGA2BFPR2FPR1HDAC6 | |
| SCHEMBL7442322 | 0.90 | ITGB3 (0.67) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 | |
| SCHEMBL8093830 | 0.89 | ITGB3 (0.60) | ITGB3ITGA2BFPR2FPR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |