Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | EYA2 | O00167 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Versetamide SCHEMBL2109367 | 1.00 | TDP1 (0.50) | TDP1BLMPMP22KDM4ELMNA | |
| Versetamide SCHEMBL15844631 | 0.98 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| Versetamide SCHEMBL23202642 | 0.98 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL8089255 | 0.98 | TDP1 (0.48) | TDP1BLMPMP22KDM4ELMNA | |
| Versetamide SCHEMBL17848990 | 0.97 | TDP1 (0.47) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL5547592 | 0.91 | BLM (0.50) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL15397125 | 0.90 | TDP1 (0.40) | TDP1BLMPMP22KDM4ELMNA | |
| Versetamide SCHEMBL237265 | 0.84 | KDM4E (0.43) | TDP1KDM4EALOX15TSHRCYP2C19 | |
| SCHEMBL24024217 | 0.84 | BLM (0.47) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL8089127 | 0.84 | BLM (0.47) | TDP1BLMPMP22KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425571-B2 | NOVEL MAGNETIC RESONANCE IMAGING AGENTS | MALLINCKRODT MEDICAL INC (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-0425571-B1 | NOVEL MAGNETIC RESONANCE IMAGING AGENTS | MALLINCKRODT INC (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5137711-A | PARAMAGNETIC DTPA AND EDTA ALKOXYALKYLAMIDE COMPLEXES AS MRI AGENTS | MALLICKRODT MEDICAL, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| US-5130120-A | Diethylenetriaminepentaacetic acid or ethylenediamine tetraacetic acid for magnetic resonance imaging | MALLINCKRODT MEDICAL, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0425571-A1 | NOVEL MAGNETIC RESONANCE IMAGING AGENTS. | MALLINCKRODT INC (US) | 1991-05-08 | — | — | EP | disclosed |
| WO-1990001024-A1 | NOVEL MAGNETIC RESONANCE IMAGING AGENTS | MALLINCKRODT, INC. (US) | 1990-02-08 | — | — | WO | disclosed |