SCHEMBL8104436

SCHEMBL8104436

CNc1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
CDK1 P06493 1/20 0.45
MAPT P10636 2/20 0.43
TP53 P04637 1/20 0.43
GLA P06280 1/20 0.43
CYP1A2 P05177 1/20 0.43
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 2/20 0.37
USP2 O75604 1/20 0.37
HDAC1 Q13547 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380195 0.89 GAA (0.54) GAACDK1MAPTTP53GLA
SCHEMBL7956556 0.88 CDK1 (0.54) GAACDK1MAPTTP53GLA
SCHEMBL9522827 0.86 GAA (0.58) GAACDK1MAPTTP53GLA
SCHEMBL9037094 0.86 GAA (0.55) GAACDK1MAPTTP53GLA
SCHEMBL11001284 0.85 GAA (0.57) GAACDK1MAPTTP53GLA
SCHEMBL8883721 0.85 GAA (0.57) GAACDK1MAPTTP53GLA
SCHEMBL9363855 0.85 GAA (0.54) GAACDK1MAPTTP53GLA
SCHEMBL9020898 0.85 GAA (0.49) GAACDK1MAPTTP53GLA
SCHEMBL9040212 0.84 GAA (0.56) GAACDK1MAPTTP53GLA
SCHEMBL10365723 0.84 GAA (0.56) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451468-B2 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA (JP) 2000-03-08 EP disclosed
US-5139565-A Herbicides which are safe for corn ISHIHARA SANGYO KAISHA LTD. (JP) 1992-08-18 US disclosed
EP-0451468-A1 Substituted pyridinesulfonamide compounds, herbicidal compositions containing them, and process for their production ISHIHARA SANGYO KAISHA, LTD. (JP) 1991-10-16 EP disclosed