Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109358 | 0.89 | KMT2A (0.47) | KMT2AALDH1A1SLC6A2MEN1CYP3A4 | |
| SCHEMBL11397979 | 0.88 | KMT2A (0.64) | KMT2ASMN1; SMN2POLBALDH1A1SLC6A2 | |
| SCHEMBL30285514 | 0.85 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2SLC6A2CYP1A2CYP3A4 | |
| SCHEMBL4533785 | 0.82 | KMT2A (0.53) | KMT2ASMN1; SMN2ALDH1A1SLC6A2MEN1 | |
| SCHEMBL17968476 | 0.81 | PPARG (0.52) | ALDH1A1SLC6A2HPGDSLC6A4SLC6A3 | |
| SCHEMBL9204554 | 0.81 | KMT2A (0.51) | KMT2ASMN1; SMN2POLBALDH1A1SLC6A2 | |
| SCHEMBL11392949 | 0.81 | KMT2A (0.50) | KMT2ASMN1; SMN2POLBALDH1A1SLC6A2 | |
| SCHEMBL8476179 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1068632 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11903287 | 0.80 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122115-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-10-16 | — | — | WO | disclosed |