Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104478 | 0.89 | KMT2A (0.57) | KMT2ASLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL4536442 | 0.84 | KDM4E (0.48) | KMT2ASLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL17968476 | 0.78 | PPARG (0.52) | SLC6A2SLC6A4SLC6A3PPARGPPARA | |
| SCHEMBL11397979 | 0.78 | KMT2A (0.64) | KMT2ASLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL9423730 | 0.75 | KMT2A (0.47) | KMT2ASLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL30285514 | 0.75 | SMN1; SMN2 (0.48) | KMT2ASLC6A2SLC6A4HRH1SLC6A3 | |
| SCHEMBL4533785 | 0.73 | KMT2A (0.53) | KMT2ASLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL21881591 | 0.73 | PPARA (0.74) | KMT2ASLC6A2SLC6A4SLC6A3PPARG | |
| SCHEMBL9423717 | 0.72 | FFAR1 (0.48) | KMT2ACYP3A4CYP2C19LMNAMEN1 | |
| SCHEMBL166380 | 0.72 | NFE2L2 (0.61) | CYP3A4CYP2C19KDM4EALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122115-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-10-16 | — | — | WO | disclosed |