Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886103 | 0.84 | PDCD1 (0.46) | PDCD1CD274KDM4ECNR2CYP1A2 | |
| SCHEMBL14156361 | 0.82 | SMN1; SMN2 (0.47) | KDM4ECYP1A2MAPTARPPARG | |
| SCHEMBL7359452 | 0.81 | PDCD1 (0.44) | PDCD1CD274KDM4ECNR2CYP1A2 | |
| SCHEMBL8119330 | 0.81 | PDCD1 (0.44) | PDCD1CD274KDM4ECNR2CYP1A2 | |
| SCHEMBL7361441 | 0.81 | FFAR1 (0.44) | PDCD1CD274KDM4EGFERKCNN4 | |
| SCHEMBL21456140 | 0.81 | PDCD1 (0.50) | PDCD1CD274KDM4ECNR2CYP1A2 | |
| SCHEMBL7464051 | 0.79 | PDCD1 (0.42) | PDCD1CD274KDM4ECNR2CYP1A2 | |
| SCHEMBL7368439 | 0.79 | PDCD1 (0.40) | PDCD1CD274KDM4ECYP1A2GRM5 | |
| SCHEMBL9512868 | 0.76 | HCRTR2 (0.48) | PDCD1CD274KDM4EMAPTHRH2 | |
| SCHEMBL7362625 | 0.76 | KCNH2 (0.46) | PDCD1CD274KDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |