Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129028 | 0.89 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL15954875 | 0.89 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL7778506 | 0.84 | TSHR (0.50) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL18681871 | 0.82 | LMNA (0.50) | TSHRL3MBTL1LMNAALDH1A1PPARG | |
| SCHEMBL17173340 | 0.82 | LMNA (0.50) | TSHRL3MBTL1LMNAALDH1A1PPARG | |
| SCHEMBL8416314 | 0.82 | LMNA (0.50) | TSHRL3MBTL1LMNAALDH1A1PPARG | |
| SCHEMBL17173344 | 0.81 | PPARG (0.49) | TSHRL3MBTL1LMNAALDH1A1PPARG | |
| SCHEMBL7794217 | 0.80 | TSHR (0.42) | TSHRL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL8897102 | 0.79 | ZDHHC7 (0.47) | TSHRL3MBTL1LMNAKMT2ARECQL | |
| SCHEMBL1706595 | 0.78 | TSHR (0.70) | TSHRLMNAALDH1A1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |