Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104838 | 0.80 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8104979 | 0.78 | CYP19A1 (0.72) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL6204558 | 0.78 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8103019 | 0.77 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL8102936 | 0.76 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP11B1TSHRCYP11B2 | |
| SCHEMBL6222574 | 0.75 | CYP19A1 (0.49) | CYP19A1CYP3A4 | |
| SCHEMBL6204190 | 0.75 | MAPT (0.57) | CYP19A1 | |
| SCHEMBL6319766 | 0.73 | MAPT (0.44) | CYP19A1 | |
| SCHEMBL6248721 | 0.72 | MAPT (0.41) | CYP19A1CYP2C19 | |
| SCHEMBL6320401 | 0.71 | MAPT (0.44) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-B1 | SELECTIVE AROMATASE INHIBITING COMPOUNDS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 2000-07-19 | — | — | EP | claimed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | claimed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | claimed |