Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | EBP | Q15125 | 2/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7923062 | 0.87 | SIGMAR1 (0.72) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL22813564 | 0.86 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL12856192 | 0.83 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL311664 | 0.82 | SIGMAR1 (0.55) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL8116673 | 0.81 | SIGMAR1 (0.58) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL19043468 | 0.80 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL19043727 | 0.80 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL7922224 | 0.80 | SIGMAR1 (0.56) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL19043653 | 0.79 | SIGMAR1 (0.55) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL2451796 | 0.78 | SIGMAR1 (0.61) | SIGMAR1EBPTMEM97EBPLABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008150486-A2 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |