Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.30 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.30 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.30 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.30 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.30 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105217 | 0.93 | AGTR1 (0.34) | AGTR1AGTR2CNR2 | |
| SCHEMBL8109296 | 0.93 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL8095792 | 0.91 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8103136 | 0.90 | AGTR1 (0.36) | AGTR1AGTR2CNR2MGLLCNR1 | |
| SCHEMBL8096084 | 0.87 | AGTR1 (0.37) | AGTR1AGTR2CNR2 | |
| SCHEMBL8111086 | 0.86 | AGTR1 (0.32) | AGTR1AGTR2 | |
| SCHEMBL8105567 | 0.85 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL8104779 | 0.85 | AGTR1 (0.30) | AGTR1AGTR2 | |
| SCHEMBL8109465 | 0.85 | AGTR1 (0.31) | AGTR1AGTR2 | |
| SCHEMBL8105251 | 0.84 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3098772-B2 | — | — | 2000-10-16 | — | — | JP | claimed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | claimed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | claimed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | disclosed |
| US-5098920-A | Hypotensive agents and treatment of congestive heart failure | G. D. SEARLE & CO. (US) | 1992-03-24 | — | — | US | disclosed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | disclosed |