Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 9/20 | 0.62 |
| ▸ | CTSG | P08311 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120831 | 0.91 | CMA1 (0.62) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL8101716 | 0.81 | CMA1 (0.75) | CMA1CTSGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13129793 | 0.80 | CMA1 (0.53) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL8116546 | 0.80 | CMA1 (0.52) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL2314943 | 0.80 | CMA1 (0.83) | CMA1CTSGMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2316175 | 0.79 | CMA1 (0.64) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL2316182 | 0.79 | CMA1 (0.64) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL8117122 | 0.79 | CMA1 (0.52) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL2310697 | 0.79 | CMA1 (0.51) | CMA1CTSGALDH1A1MEN1KMT2A | |
| SCHEMBL8122295 | 0.78 | CMA1 (0.75) | CMA1CTSGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152674-B1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2008147697-A1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-12-04 | — | — | WO | disclosed |