SCHEMBL8105403

SCHEMBL8105403

O=CN(c1ccc(F)cc1)c1cccc(Oc2csc(C(F)(F)F)c2)n1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
ATM Q13315 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8111969 0.92
SCHEMBL8123653 0.89 POLB (0.33) POLBATM
SCHEMBL8119917 0.88
SCHEMBL8118508 0.87 POLB (0.31) POLBATM
SCHEMBL8119408 0.87 POLB (0.33) POLBATM
SCHEMBL8118897 0.86 POLB (0.33) POLBATMMAPT
SCHEMBL8126135 0.81 MAPT (0.34) POLBMAPT
SCHEMBL8092120 0.81 ALDH1A1 (0.32) POLBMAPT
SCHEMBL8126094 0.80 ALDH1A1 (0.32) POLBMAPT
SCHEMBL8125993 0.80 MAPT (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP claimed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO claimed
US-5869426-A Herbicidal 6-thienyloxypyrid-2-carboxamides AMERICAN CYANAMID COMPANY (US) 1999-02-09 US claimed
EP-1028959-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 2000-08-23 EP disclosed
US-6080861-A MAKING A 2-SUBSTITUTED,4-HYDROXYTHIOPHENE CHEMICAL INTERMEDIATE TO HERBICIDES VIA SAPONIFICATION OF 5-ALKOXYCARBONYL, OPTIONALLY HYDROXY-PROTECTED ANALOG FOLLOWED BY DECARBOXYLATION AMERICAN CYANAMID COMPANY (US) 2000-06-27 US disclosed
WO-1999024427-A1 HERBICIDAL FURANYL- AND THIENYLOXYAZINES AMERICAN CYANAMID COMPANY (US) 1999-05-20 WO disclosed
US-5869426-A Herbicidal 6-thienyloxypyrid-2-carboxamides AMERICAN CYANAMID COMPANY (US) 1999-02-09 US disclosed