Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044368 | 1.00 | TSHR (0.45) | TSHRALDH1A1KMT2ATP53MAPT | |
| SCHEMBL7815856 | 0.83 | TSHR (0.44) | TSHRALDH1A1KMT2ATP53MAPT | |
| SCHEMBL7815857 | 0.83 | TSHR (0.44) | TSHRALDH1A1KMT2ATP53MAPT | |
| SCHEMBL1042756 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1TP53MAPTHIF1A | |
| SCHEMBL29481810 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1TP53MAPTHIF1A | |
| SCHEMBL1044996 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1TP53MAPTHIF1A | |
| SCHEMBL17861527 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1TP53MAPTHIF1A | |
| SCHEMBL909731 | 0.79 | TSHR (0.47) | TSHRALDH1A1KMT2ATP53MAPT | |
| SCHEMBL6979170 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1KMT2ATP53HPGD | |
| SCHEMBL1021560 | 0.79 | PTGDR2 (0.55) | TSHRALDH1A1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136825-A | ANTIDEPRESSANTS AND CENTRAL NERVOUS SYSTEM AGENTS | KNOLL AKTIENGESELLSCHAFT | 2000-10-24 | — | — | US | disclosed |