Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559331 | 0.86 | FPR2 (0.44) | FPR2PROKR1MMP1TACR3 | |
| SCHEMBL5418879 | 0.84 | HRH3 (0.48) | FPR2PROKR1HRH3KCNH2MMP1 | |
| SCHEMBL30843204 | 0.78 | FPR2 (0.49) | FPR2PROKR1HRH3KCNH2MMP1 | |
| SCHEMBL17339936 | 0.77 | FPR2 (0.57) | FPR2PROKR1HRH3MMP1NAMPT | |
| SCHEMBL20069052 | 0.75 | HRH3 (0.56) | FPR2PROKR1HRH3MMP1 | |
| SCHEMBL4051291 | 0.75 | FPR2 (0.47) | FPR2PROKR1HRH3KCNH2MMP1 | |
| SCHEMBL7956692 | 0.75 | FPR2 (0.47) | FPR2PROKR1HRH3KCNH2MMP1 | |
| SCHEMBL16839481 | 0.74 | FPR2 (0.46) | FPR2PROKR1HRH3KCNH2MMP1 | |
| SCHEMBL13432144 | 0.73 | HRH3 (0.52) | FPR2PROKR1HRH3KCNH2NAMPT | |
| SCHEMBL3385980 | 0.73 | HRH3 (0.50) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |