Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | MAOA | P21397 | 6/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | SDHA | P31040 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105445 | 1.00 | MAOB (0.57) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL8105406 | 0.89 | MAOA (0.63) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL8105405 | 0.89 | MAOA (0.63) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL14042561 | 0.85 | MAOA (0.65) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL7839110 | 0.85 | MAOA (0.67) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL7839112 | 0.85 | MAOA (0.67) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL8105423 | 0.82 | MAOA (0.58) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL8105430 | 0.82 | MAOA (0.58) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL13054906 | 0.82 | MAOA (0.62) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL14042554 | 0.82 | MAOA (0.62) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |