Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.61 |
| ▸ | MAOB | P27338 | 11/20 | 0.48 |
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SDHA | P31040 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105780 | 1.00 | CALML3 (0.61) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5328084 | 0.89 | CALML3 (0.47) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5328092 | 0.89 | CALML3 (0.47) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL7838905 | 0.85 | MAOA (0.68) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL7838909 | 0.85 | MAOA (0.68) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14540794 | 0.85 | MAOB (0.48) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8111378 | 0.83 | CALML3 (0.61) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL8111373 | 0.83 | CALML3 (0.61) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL1557035 | 0.83 | CALML3 (0.66) | CALML3MAOBMAOACYP2C19CYP2C9 | |
| SCHEMBL7831813 | 0.82 | CALML3 (0.65) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1075073-C | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials | UPJOHN CO (US) | 2001-11-21 | — | — | CN | disclosed |
| US-6124334-A | A BACTERICIDE TREATING INFECTIONS CAUSED BY GRAM-POSITIVE AEROBIC BACTERIA SUCH AS STAPHYLOCOCCUS, STREPTOCOCCUS AND ENTEROCOCCUS AS WELL AS ANAEROBIC ORGANISMS SUCH AS BACTEROIDES AND CLOSTRIDIUM AND MYCOBACTERIDIUM | PHARMACIA & UPJOHN COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| US-5910504-A | BACTERICIDES TREATING INFECTIONS | PHARMACIA & UPJOHN (US) | 1999-06-08 | — | — | US | disclosed |
| CN-1172484-A | Phenyl oxazolidinone antibacterial agents substituted with heteroaromatic rings | UPJOHN CO (US) | 1998-02-04 | — | — | CN | disclosed |