Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099195 | 0.76 | HCAR3 (0.36) | HCAR3HCAR2CCR2TACR1OPRM1 | |
| SCHEMBL8103222 | 0.74 | KDM1A (0.41) | KDM1AHCAR3HCAR2CCR2CHRM3 | |
| SCHEMBL10728986 | 0.66 | KDM1A (0.39) | KDM1AHCAR3HCAR2CCR2TACR1 | |
| SCHEMBL10731891 | 0.64 | HCAR3 (0.40) | KDM1AHCAR3HCAR2CCR2TACR1 | |
| SCHEMBL11812241 | 0.63 | SLC6A4 (0.47) | KDM1ACCR2TACR1OPRM1OPRL1 | |
| SCHEMBL10468722 | 0.62 | KDM1A (0.54) | KDM1ACCR2OPRM1OPRL1GRIN2B | |
| SCHEMBL8089737 | 0.62 | PBRM1 (0.43) | KDM1AMAPTHTTCES2LMNA | |
| SCHEMBL11466478 | 0.62 | HCAR3 (0.45) | KDM1AHCAR3HCAR2CCR2OPRM1 | |
| SCHEMBL696251 | 0.61 | AKR1C3 (0.67) | KDM1ACCR2OPRM1OPRL1MAPT | |
| SCHEMBL11811786 | 0.61 | SLC6A4 (0.48) | KDM1ACCR2OPRM1OPRL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |