SCHEMBL8105842

SCHEMBL8105842

CCCCc1cn(-c2c(Cl)cccc2CCC)c(=O)n1Cc1ccc(-c2ncccc2-c2nnn[nH]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 10/20 0.46
AGTR2 P50052 10/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123565 0.96 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL8118654 0.96 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL8120906 0.95 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL8116857 0.94 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL8125401 0.94 AGTR1 (0.52) AGTR1AGTR2
SCHEMBL8110766 0.93 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL8117225 0.93 AGTR1 (0.50) AGTR1AGTR2
SCHEMBL8119946 0.93 AGTR1 (0.51) AGTR1AGTR2
SCHEMBL8125390 0.92 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL8124331 0.92 AGTR1 (0.54) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0664802-B1 N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS SEARLE & CO (US) 2000-03-15 EP disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed