Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6340007 | 0.99 | SIGMAR1 (0.56) | SIGMAR1HRH3CYP2D6ACHEHRH1 | |
| SCHEMBL6338919 | 0.85 | SIGMAR1 (0.54) | SIGMAR1HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL6338916 | 0.84 | SIGMAR1 (0.53) | SIGMAR1HRH3HRH1POLB | |
| Hydrochloric Acid SCHEMBL6347775 | 0.83 | SIGMAR1 (0.59) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL6341471 | 0.83 | SIGMAR1 (0.76) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL6340108 | 0.83 | SIGMAR1 (0.59) | SIGMAR1HRH3ACHE | |
| Hydrochloric Acid SCHEMBL6339528 | 0.83 | SIGMAR1 (0.58) | SIGMAR1HRH3 | |
| SCHEMBL4130604 | 0.83 | SIGMAR1 (0.58) | SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL6338969 | 0.82 | SIGMAR1 (0.50) | SIGMAR1MAPT | |
| SCHEMBL8108039 | 0.81 | SIGMAR1 (0.57) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056733-A1 | HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042458-A1 | HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-08-26 | — | — | WO | disclosed |