Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105950 | 1.00 | PTGDR2 (0.42) | PTGDR2PKMPKLRCNR2PARP14 | |
| SCHEMBL8109510 | 0.77 | PKM (0.48) | PTGDR2PKMPKLRCNR2PARP14 | |
| SCHEMBL24712032 | 0.74 | PKM (0.50) | PTGDR2PKMPKLRCNR2PARP14 | |
| SCHEMBL3921892 | 0.73 | KDM4E (0.58) | PTGDR2PKMPKLRNPC1RAB9A | |
| SCHEMBL1847833 | 0.71 | PKM (0.56) | PKMPKLRNPC1RAB9AGAA | |
| SCHEMBL6616459 | 0.70 | TSHR (0.56) | PKMPKLRNPC1RAB9AMEN1 | |
| SCHEMBL14040701 | 0.69 | PKM (0.46) | PTGDR2PKMPKLRCNR2PARP14 | |
| SCHEMBL240108 | 0.69 | MEN1 (0.49) | PTGDR2PKMNPC1RAB9AMEN1 | |
| SCHEMBL6081652 | 0.69 | HRH3 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6081647 | 0.69 | HRH3 (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136825-A | ANTIDEPRESSANTS AND CENTRAL NERVOUS SYSTEM AGENTS | KNOLL AKTIENGESELLSCHAFT | 2000-10-24 | — | — | US | disclosed |