Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17047296 | 1.00 | ATM (0.40) | ATMCTSKCTSLCTSBHCAR2 | |
| SCHEMBL8101633 | 0.98 | ATM (0.41) | ATMCTSKCTSLCTSBHCAR2 | |
| SCHEMBL17047299 | 0.94 | HCAR2 (0.46) | ATMCTSKCTSLCTSBHCAR2 | |
| SCHEMBL17047297 | 0.94 | HCAR2 (0.46) | ATMCTSKCTSLCTSBHCAR2 | |
| SCHEMBL8099571 | 0.93 | ATM (0.40) | ATMCTSKCTSLCTSBHCAR2 | |
| SCHEMBL1648754 | 0.87 | TSHR (0.43) | ATMCTSKCTSLCTSBMEN1 | |
| SCHEMBL29117687 | 0.87 | TSHR (0.43) | ATMCTSKCTSLCTSBMEN1 | |
| SCHEMBL4401693 | 0.85 | TSHR (0.44) | ATMCTSKCTSLCTSBMEN1 | |
| SCHEMBL11640875 | 0.84 | MEN1 (0.37) | CTSKCTSLCTSBMEN1KMT2A | |
| SCHEMBL28238660 | 0.82 | CTSK (0.45) | CTSKCTSLCTSBKMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006130-A1 | Fumaric acid diester resin composition, cross-linked fumaric acid diester resin and process | NOF CORPORATION (JP) | 2000-06-07 | — | — | EP | disclosed |