Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30640814 | 0.80 | HTT (0.47) | NPC1RAB9AHPGDMAPK1HTT | |
| SCHEMBL28503016 | 0.77 | MAPK1 (0.44) | SKP2NPC1RAB9AHPGDMAPK1 | |
| SCHEMBL22284266 | 0.77 | NPSR1 (0.40) | NPC1RAB9AHPGDMAPK1HTT | |
| SCHEMBL840773 | 0.76 | SMN1; SMN2 (0.38) | MAPK1NPSR1HTR1DMAPTTSHR | |
| SCHEMBL27467179 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CNR1CNR2CYP2C9 | |
| SCHEMBL28416156 | 0.73 | PTGS2 (0.53) | HTTGPR84MAPTTSHRTP53 | |
| SCHEMBL2163573 | 0.73 | HSPA5 (0.43) | NPC1RAB9AHPGDMAPK1HTT | |
| SCHEMBL5503406 | 0.72 | SKP2 (0.37) | SKP2NPC1RAB9AHPGDMAPK1 | |
| SCHEMBL22284270 | 0.72 | NPSR1 (0.37) | NPC1RAB9AHPGDMAPK1HTT | |
| SCHEMBL11340841 | 0.72 | SKP2 (0.43) | SKP2NPC1RAB9AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031015-A | POLYMERIZABLE POLYESTER OF 1-10 REPEATING UNITS BEING MODIFIED ON BOTH ENDS BY A HYDROXYALKYL (METH)ACRYLATE; SHRINKAGE INHIBITION; LOW VISCOSITY; MECHANICAL STRENGTH; CAN INCLUDE MORE FILLER THAN USUAL | IVOCLAR AG (LI) | 2000-02-29 | — | — | US | disclosed |