Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12173556 | 0.94 | PDE7A (0.37) | PDE7ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6898 | 0.92 | HTR2A (0.35) | PDE7ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL31459757 | 0.92 | HTR2A (0.35) | PDE7ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1766226 | 0.84 | OPRM1 (0.36) | PDE7AHTR2AHTR2COPRM1 | |
| SCHEMBL31582660 | 0.84 | HCRTR2 (0.35) | HTR2AHTR2COPRM1 | |
| Hydrochloric Acid SCHEMBL1766235 | 0.82 | OPRM1 (0.35) | HTR2AHTR2COPRM1 | |
| SCHEMBL2289999 | 0.82 | MEN1 (0.38) | PDE7AALDH1A1MEN1KMT2AHTR2A | |
| SCHEMBL30168408 | 0.82 | MEN1 (0.38) | PDE7AALDH1A1MEN1KMT2AHTR2A | |
| SCHEMBL25001784 | 0.80 | POLB (0.35) | ALDH1A1 | |
| SCHEMBL29813458 | 0.79 | HTR2A (0.33) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |