Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 4/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595418 | 1.00 | ABCB1 (0.35) | ABCB1NR1H2IDO1PRMT5WDR77 | |
| SCHEMBL8108567 | 0.91 | ABCB1 (0.34) | ABCB1NR1H2CCR2HTRA1 | |
| SCHEMBL9595613 | 0.91 | ABCB1 (0.34) | ABCB1NR1H2CCR2HTRA1 | |
| SCHEMBL8107520 | 0.90 | NR1H2 (0.34) | ABCB1NR1H2CCR2SRC | |
| SCHEMBL4669448 | 0.88 | NR1H2 (0.35) | ABCB1NR1H2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL7451687 | 0.88 | NR1H2 (0.35) | ABCB1NR1H2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL4669615 | 0.88 | NR1H2 (0.35) | ABCB1NR1H2ALDH1A1CHRM2CHRM1 | |
| SCHEMBL9596179 | 0.88 | ABCB1 (0.36) | ABCB1NR1H2IDO1 | |
| SCHEMBL9596361 | 0.88 | ABCB1 (0.36) | ABCB1NR1H2IDO1 | |
| SCHEMBL12431668 | 0.87 | NR1H2 (0.37) | ABCB1NR1H2ALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |