SCHEMBL9596179

SCHEMBL9596179

COC(=O)C(O)C[C@H]1C[C@@H](O[Si](C)(C)C(C)(C)C)CN1C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.36
NR1H2 P55055 1/20 0.31
UCHL1 P09936 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9596361 1.00 ABCB1 (0.36) ABCB1NR1H2UCHL1IDO1
SCHEMBL9595521 0.90 ABCB1 (0.34) ABCB1NR1H2
SCHEMBL9595177 0.88 ABCB1 (0.34) ABCB1NR1H2
SCHEMBL9595611 0.88 ABCB1 (0.34) ABCB1NR1H2
SCHEMBL9595418 0.88 ABCB1 (0.35) ABCB1NR1H2IDO1
SCHEMBL8106554 0.88 ABCB1 (0.35) ABCB1NR1H2IDO1
SCHEMBL9596433 0.83 ABCB1 (0.31) ABCB1IDO1
SCHEMBL12431668 0.82 NR1H2 (0.37) ABCB1NR1H2
SCHEMBL8107520 0.82 NR1H2 (0.34) ABCB1NR1H2
SCHEMBL12519787 0.82 NR1H2 (0.33) ABCB1NR1H2UCHL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993011128-A1 AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-10 WO disclosed