Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113960 | 0.88 | NR1H2 (0.36) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL8107705 | 0.87 | UCHL1 (0.36) | UCHL1NR1H2HSD17B10CYP1A2POLB | |
| SCHEMBL30987695 | 0.85 | UCHL1 (0.35) | UCHL1NR1H2HSD17B10CYP1A2POLB | |
| SCHEMBL8107580 | 0.84 | UCHL1 (0.34) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL8107709 | 0.83 | UCHL1 (0.36) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL8098433 | 0.82 | UCHL1 (0.33) | UCHL1NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL4300613 | 0.82 | UCHL1 (0.37) | UCHL1NR1H2HSD17B10CYP1A2POLB | |
| SCHEMBL2809688 | 0.82 | UCHL1 (0.39) | UCHL1NR1H2HSD17B10CYP1A2POLB | |
| SCHEMBL3832181 | 0.82 | UCHL1 (0.39) | UCHL1NR1H2HSD17B10CYP1A2POLB | |
| SCHEMBL2708045 | 0.82 | UCHL1 (0.39) | UCHL1NR1H2HSD17B10CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |