Morpholine

Morpholine

SCHEMBL8106569

C1COCCN1.CCCCCCCCCCCCCCCl

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 1/20 0.54
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
CYP2C9 P11712 1/20 0.44
TDP1 Q9NUW8 1/20 0.40
GNAI3 P08754 11/20 0.35
GNAO1 P09471 11/20 0.35
GNAI1 P63096 11/20 0.35
THRB P10828 1/20 0.33
EPHX1 P07099 1/20 0.32
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL11540752 1.00 TSHR (0.54) TSHRALDH1A1MEN1KMT2AKDM4E
Morpholine SCHEMBL5414836 1.00 TSHR (0.54) TSHRALDH1A1MEN1KMT2AKDM4E
Morpholine SCHEMBL27498050 0.98 TSHR (0.50) TSHRALDH1A1MEN1KMT2AKDM4E
Morpholine SCHEMBL7104908 0.91 TSHR (0.45) TSHRALDH1A1MEN1KMT2AKDM4E
Octane SCHEMBL28745870 0.89 MEN1 (0.55) TSHRALDH1A1MEN1KMT2AKDM4E
Nonane SCHEMBL5317273 0.89 MEN1 (0.55) TSHRALDH1A1MEN1KMT2AKDM4E
Tridecane SCHEMBL27548937 0.89 MEN1 (0.55) TSHRALDH1A1MEN1KMT2AKDM4E
Dodecane SCHEMBL28778960 0.89 MEN1 (0.55) TSHRALDH1A1MEN1KMT2AKDM4E
Heptane SCHEMBL28288362 0.89 MEN1 (0.55) TSHRALDH1A1MEN1KMT2AKDM4E
Morpholine SCHEMBL27362751 0.87 MEN1 (0.58) TSHRMEN1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1012134-A1 QUATERNARY AMMONIUM PHOSPHATE COMPOUNDS AND METHOD OF PREPARING THE SAME SK Chemicals (KR) 2000-06-28 EP disclosed
WO-1999012889-A1 QUATERNARY AMMONIUM PHOSPHATE COMPOUND AND METHOD OF PREPARING THE SAME SK CHEMICALS (KR) 1999-03-18 WO disclosed