⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067759 | 0.68 | — | — | |
| SCHEMBL8100816 | 0.68 | — | — | |
| SCHEMBL2363208 | 0.62 | CHEK1 (0.36) | — | |
| SCHEMBL11135809 | 0.59 | — | — | |
| SCHEMBL8991888 | 0.58 | POLB (0.31) | — | |
| SCHEMBL15777593 | 0.58 | CYP3A4 (0.31) | — | |
| SCHEMBL11766523 | 0.58 | XDH (0.31) | — | |
| SCHEMBL8516382 | 0.58 | — | — | |
| SCHEMBL6049027 | 0.58 | — | — | |
| SCHEMBL19306392 | 0.57 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36831-E | TREATMENT OF IRON DEFICIENCY ANEMIA | BRITISH TECHNOLOGY GROUP LTD. (GB) | 2000-08-22 | — | — | US | claimed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | claimed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | claimed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | claimed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | claimed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | claimed |