Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399996 | 0.95 | DPP8 (0.36) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL8108227 | 0.93 | DPP8 (0.38) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL8106599 | 0.85 | DPP8 (0.42) | DPP8DPP9ALDH1A1MAPTTGM2 | |
| SCHEMBL9596597 | 0.83 | ABCB1 (0.42) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL8112463 | 0.82 | ABCB1 (0.39) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL9605060 | 0.82 | DPP8 (0.34) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL8106387 | 0.81 | DPP8 (0.43) | DPP8DPP9ALDH1A1MAPTTGM2 | |
| SCHEMBL9019973 | 0.80 | MAPT (0.37) | ALDH1A1MAPTHPGDCCR5SMN1; SMN2 | |
| SCHEMBL9847187 | 0.80 | DPP8 (0.38) | DPP8DPP9ABCB1ALDH1A1MAPT | |
| SCHEMBL9847186 | 0.80 | DPP8 (0.38) | DPP8DPP9ABCB1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |