Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847187 | 1.00 | DPP8 (0.38) | DPP8DPP9MAPTALDH1A1CCR5 | |
| SCHEMBL10390672 | 0.84 | GAA (0.45) | DPP8DPP9MAPTALDH1A1GAA | |
| SCHEMBL10390670 | 0.84 | GAA (0.45) | DPP8DPP9MAPTALDH1A1GAA | |
| SCHEMBL9365346 | 0.81 | DPP8 (0.39) | DPP8DPP9MAPTALDH1A1CCR5 | |
| SCHEMBL9365352 | 0.81 | DPP8 (0.39) | DPP8DPP9MAPTALDH1A1CCR5 | |
| SCHEMBL9020242 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1CCR5HPGDSMN1; SMN2 | |
| SCHEMBL9520614 | 0.81 | MMP2 (0.43) | MAPTALDH1A1CCR5HPGDGAA | |
| SCHEMBL8108227 | 0.80 | DPP8 (0.38) | DPP8DPP9MAPTALDH1A1CCR5 | |
| SCHEMBL9605061 | 0.80 | ABCB1 (0.39) | DPP8DPP9MAPTALDH1A1CCR5 | |
| SCHEMBL8923324 | 0.80 | ALDH1A1 (0.40) | MAPTALDH1A1CCR5HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435320-A1 | 2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |