SCHEMBL8106856

SCHEMBL8106856

CCCCCCCCC1(CCCCCCCC)OC(=O)CC(=O)O1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.45
PTPN1 P18031 7/20 0.41
CDC25B P30305 5/20 0.41
ACP1 P24666 4/20 0.39
PRKCA P17252 6/20 0.38
CYP1A2 P05177 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8105861 1.00 SIRT2 (0.45) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL8120957 1.00 SIRT2 (0.45) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL8113804 0.98 SIRT2 (0.42) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL8116363 0.92 SIRT2 (0.37) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL8114959 0.83 SIRT2 (0.32) SIRT2PTPN1CDC25B
SCHEMBL17064162 0.82 SIRT2 (0.44) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL5924306 0.76 SIRT2 (0.42) SIRT2PTPN1CDC25BACP1PRKCA
SCHEMBL8049835 0.75 PTPN1 (0.36) SIRT2PTPN1CDC25B
SCHEMBL22712666 0.74 SIRT2 (0.34) SIRT2PTPN1CDC25BCYP1A2
SCHEMBL21428296 0.73 KMT2A (0.41) SIRT2PTPN1CDC25BACP1PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed