Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | CDC25B | P30305 | 5/20 | 0.39 |
| ▸ | ACP1 | P24666 | 4/20 | 0.36 |
| ▸ | PRKCA | P17252 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106856 | 0.98 | SIRT2 (0.45) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL8120957 | 0.98 | SIRT2 (0.45) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL8105861 | 0.98 | SIRT2 (0.45) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL8116363 | 0.94 | SIRT2 (0.37) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL8114959 | 0.85 | SIRT2 (0.32) | SIRT2PTPN1CDC25B | |
| SCHEMBL17064162 | 0.80 | SIRT2 (0.44) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL8049835 | 0.77 | PTPN1 (0.36) | SIRT2PTPN1CDC25B | |
| SCHEMBL22712666 | 0.76 | SIRT2 (0.34) | SIRT2PTPN1CDC25BCYP1A2ALDH1A1 | |
| SCHEMBL21428296 | 0.75 | KMT2A (0.41) | SIRT2PTPN1CDC25BACP1PRKCA | |
| SCHEMBL2710911 | 0.75 | PTPN1 (0.40) | PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123581-A1 | EMULSION POLYMERS OF 1,1-DICARBONYL 1-ALKENES OF CONTROLLED PARTICLE SIZE | SIRRUS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020123579-A1 | POLYMERIZATION OF 1,1-DICARBONYL 1-ALKENES | SIRRUS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |