Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106891 | 1.00 | ACACB (0.32) | ACACBPPARDPPARAGRM3MMP13 | |
| SCHEMBL8111012 | 0.91 | PPARD (0.33) | PPARDPPARA | |
| SCHEMBL8111015 | 0.91 | PPARD (0.33) | PPARDPPARA | |
| SCHEMBL8097538 | 0.90 | CYP3A4 (0.34) | ACACBKCNH2ALDH1A1HTT | |
| SCHEMBL8097541 | 0.90 | CYP3A4 (0.34) | ACACBKCNH2ALDH1A1HTT | |
| SCHEMBL8105299 | 0.89 | ACACB (0.34) | ACACBPPARDPPARAGRM3ALDH1A1 | |
| SCHEMBL8105302 | 0.89 | ACACB (0.34) | ACACBPPARDPPARAGRM3ALDH1A1 | |
| SCHEMBL8107270 | 0.84 | HTT (0.33) | ACACBPPARDPPARAHTT | |
| SCHEMBL8107272 | 0.84 | HTT (0.33) | ACACBPPARDPPARAHTT | |
| SCHEMBL8540628 | 0.83 | ACACB (0.32) | ACACBPPARDPPARAMMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033367-A2 | Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5677464-A | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0687672-A2 | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |