Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795890 | 0.82 | KMT2A (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL30478066 | 0.82 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29490361 | 0.82 | MEN1 (0.59) | KMT2AMEN1TDP1POLB | |
| SCHEMBL29766665 | 0.82 | AKR1C3 (0.56) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL133823 | 0.82 | AKR1C3 (0.56) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL474709 | 0.82 | KMT2A (0.70) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2475659 | 0.82 | MEN1 (0.59) | KMT2AMEN1TDP1POLB | |
| SCHEMBL5340030 | 0.82 | MEN1 (0.89) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14641620 | 0.82 | KMT2A (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7768635 | 0.82 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59075966-A | — | — | None | — | — | JP | disclosed |
| CN-109320513-A | A method of synthesis Trimetinib | 安庆奇创药业有限公司 | 2019-02-12 | — | — | CN | disclosed |
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |
| US-6096842-A | Aerobically curable adhesive | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-08-01 | — | — | US | disclosed |
| US-4598092-A | FUNGICIDES FOR PLANTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4507284-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-03-26 | — | — | US | disclosed |
| EP-0063464-B1 | FUNGICIDAL COMPOSITION COMPRISING ALPHA-SUBSTITUTED ETHYLPHOSPHINIC ACIDS OR THEIR SALTS, AND METHOD OF PREVENTING OR CURING PLANT DISEASE USING THEM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-20 | — | — | EP | disclosed |
| US-4473561-A | Fungicidal composition comprising alpha-substituted ethylphosphinic acids or their salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-09-25 | — | — | US | disclosed |
| EP-0113190-A1 | Alpha-hydroxy-beta-haloethylphosphinic acids and their salts, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-07-11 | — | — | EP | disclosed |
| JP-S5975966-A | WATER-BASE INK FOR INK JET PRINTING | RICOH CO LTD | 1984-04-28 | — | — | JP | disclosed |
| EP-0031054-B1 | SOIL DISINFECTANT COMPOSITION, A METHOD FOR PREVENTING AND CONTROLLING DISEASES IN SOIL AND CERTAIN PHENYLPHOSPHINIC ACID SALTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-02-29 | — | — | EP | disclosed |
| EP-0013996-B1 | REACTIVE AZO COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR DYEING FIBERS AND TEXTILES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-12-14 | — | — | EP | disclosed |
| US-4366150-A | SATURATED HETEROCYCLIC AMINE SALT OF PHENYLPHOSPHINIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-12-28 | — | — | US | disclosed |
| EP-0063464-A1 | Fungicidal composition comprising alpha-substituted ethylphosphinic acids or their salts, and method of preventing or curing plant disease using them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-10-27 | — | — | EP | disclosed |
| EP-0031054-A1 | Soil disinfectant composition, a method for preventing and controlling diseases in soil and certain phenylphosphinic acid salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-07-01 | — | — | EP | disclosed |
| US-3979412-A | Process for producing 3-anilino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JA) | 1976-09-07 | — | — | US | disclosed |
| US-3933874-A | Method for preparing of β-anilino-β-hydrazinoacrylates | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | disclosed |