Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.76 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107902 | 0.90 | KDM4E (0.72) | KDM4ESLC2A1ALDH1A1AKR1B1POLB | |
| SCHEMBL432503 | 0.90 | SLC2A1 (0.78) | KDM4ESLC2A1ALDH1A1AKR1B1POLB | |
| SCHEMBL426292 | 0.86 | KDM4E (0.72) | KDM4ESLC2A1ALDH1A1AKR1B1POLB | |
| SCHEMBL8115968 | 0.86 | SLC2A1 (0.60) | KDM4ESLC2A1ALDH1A1AKR1B1POLB | |
| SCHEMBL8107875 | 0.86 | KDM4E (1.00) | KDM4ESLC2A1ALDH1A1AKR1B1MEN1 | |
| SCHEMBL24496704 | 0.83 | SLC2A1 (0.72) | KDM4ESLC2A1ALDH1A1AKR1B1MEN1 | |
| SCHEMBL5322779 | 0.82 | KDM4E (0.76) | KDM4ESLC2A1ALDH1A1AKR1B1MEN1 | |
| SCHEMBL8115506 | 0.81 | SLC2A1 (0.73) | KDM4ESLC2A1ALDH1A1AKR1B1MEN1 | |
| SCHEMBL10459171 | 0.79 | SLC2A1 (0.71) | KDM4ESLC2A1ALDH1A1AKR1B1MEN1 | |
| SCHEMBL4254491 | 0.79 | KDM4E (0.72) | KDM4ESLC2A1ALDH1A1AKR1B1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |