Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | BCL9 | O00512 | 3/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860691 | 0.82 | F2 (0.47) | DDR1RORCF2F10 | |
| Trifluoroacetic Acid SCHEMBL841558 | 0.79 | F7 (0.45) | DDR1F2F10 | |
| SCHEMBL860387 | 0.72 | F2 (0.53) | DDR1F2F10 | |
| SCHEMBL3680501 | 0.71 | DDR1 (0.44) | DDR1F2F10 | |
| SCHEMBL860972 | 0.68 | F2 (0.49) | F2F10 | |
| SCHEMBL860322 | 0.67 | F2 (0.56) | F2F10 | |
| SCHEMBL16603459 | 0.67 | RORC (0.52) | DDR1RORCBCL9CTNNB1 | |
| SCHEMBL16605519 | 0.67 | BCL9 (0.52) | BCL9CTNNB1 | |
| SCHEMBL860343 | 0.66 | F7 (0.48) | F2F10 | |
| SCHEMBL860902 | 0.66 | F2 (0.52) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007015-A1 | MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY | SANOFI-AVENTIS (FR) | 2009-01-15 | — | — | WO | disclosed |